Preheat the oven to broil. Rinse poblano peppers and place on a baking sheet lined with foil and place under the broiler for 10-15 minutes, flipping a few times to blacken the skins and roast the peppers. Reduce oven to 350 and place the charred peppers in a bowl covered with a towel and allow to steam for 10 minutes.
Stem and seed the peppers and rub off the charred skin as much as you can. Finely chop the peppers (or leave a bit larger dice if you like).
Cook the pasta according to the directions but subtract 2 minutes. Drain and rinse under cold water and toss with a little oil until ready to use.
In a saucepan, heat the butter until melted, then whisk in the flour. Cook for a minute or two, whisking gently. Slowly add the milk/cream while whisking, a little at a time to prevent lumps. Whisk in the mustard, mascarpone, cajun spice, paprika and salt and some fresh black pepper to taste. Remove from heat and bit by bit whisk in the cheeses. Place back onto the heat and whisk until smooth. Season with more salt if needed, then add the chopped poblanos.
Pour the sauce onto the cooked pasta and mix well. Pour into a deep dish pie plate or a 9x13 pan or whatever you want to bake it in. Spread the panko on top and bake for 30 minutes. Heat the broiler again and broil the top until the breadcrumbs are lightly browned, then remove from the oven.
Cool for 5 minutes then serve.